Micoral Oral Gel

Unit Price: ৳ 67.50

Indications of  Micoral Oral Gel

Micoral oral gel is indicated in the treatment and prevention of fungal infections of the oropharynx and gastrointestinal tract and of superinfections due to gram positive bacteria, including oral candidosis and denture stomatitis. Also indicated in prophylactic management of patients at high risk from opportunistic fungal infection.

Pharmacology of  Micoral Oral Gel

Micoral oral gel is the preparation of Miconazole. It is a synthetic imidazole which exhibits broad spectrum activity against pathogenic dermatophytes, including Trichophyton species and yeasts including Candida species, Cryptococcus neoformans, Coccidioides immitis and Paracoccidioides brasiliensis as well range of gram-positive cocci and bacilli. It acts by inhibiting membrane sterol synthesis and interfering with the permeability of the fungal cell membranes. as

Dosage & Administration of  Micoral Oral Gel

  • For oral administration: Dosage is based on 15 mg/kg/day.
  • Infants under 2 years: Half spoonful (2.5 ml) of gel twice daily.
  • Children aged 2-6 years: One spoonful (5 ml) of gel twice daily.
  • Children aged 6 years and over: One spoonful (5 ml) of gel four times daily.
  • Adult patients: One or two spoonfuls (5-10 ml) of gel four times daily.


In case of localized lessions of the mouth, a small amount of gel may be applied directly to the affected area with a clean finger, 2-4 times a day. For best results Micoral oral gel should be kept in contact with the affected area as long as possible. The treatment should be continued for up to two days after symptoms have cleared. For oral candidiasis, dental prosthesis should be removed at night and brushed with the gel. Elderly patients: Same as adult dose.

Contraindication of Micoral Oral Gel

Miconazole is contraindicated in patients with known hypersensitivity to the active ingredient.

Side effects of  Micoral Oral Gel

Occasionally, nausea and vomiting, diarrhoea with long term use, rarely allergic reactions, isolated reports of hepatitis.

Overdosage of  Micoral Oral Gel

In general Miconazole is not highly toxic. Accidental overdosage may cause vomiting and diarrhoea.

Interaction of  Micoral Oral Gel

Miconazole can inhibit the metabolism of drugs metabolized by the Cytochrome P450-3A and 2C9 families. Miconazole oral gel should not be used during treatment with cisapride, trizolam, oral midazolam, mizolastine, quinidine, simvastatin and lovastatin.

Precautions & Warnings of  Micoral Oral Gel

If the concomitant use of Miconazole and Anticoagulant is considered, the anti- coagulant effect should be monitored and titrated. Miconazole and Phenytoin level should also be monitored when used concomitantly. In infants and young children, caution must be taken to ensure that the gel does not obstruct the throat. Hence, the gel should not applied to the back of the throat and the full dose should be divided into smaller portions.

Use of Micoral Oral Gel in Pregnancy

There is no information concerning the safety of Miconazole oral gel during pregnancy. So Miconazole oral gel should be avoided in pregnant women if possible. The potential bazards should be balanced against the possible benefits. As many drugs are ed to and in human milk, cauned should be exercised when Miconazole is administered a nursing woman.

Pharmaceutical Precautions of  Micoral Oral Gel

Store in a cool (below 30°C) & dry place. Protect from light.

Commercial Pack of  Micoral Oral Gel

Micoral oral gel: Tube of 15 g & 30 g.