Itracon Capsule

Unit Price: ৳ 16.00

Indications of Itracon

Itracon 100 mg provides effective treatment for various fungal infections, including

  • Tinea corporis,
  • Tinea cruris,
  • Tinea pedis,
  • Tinea manuum,
  • Vulvovaginal candidiasis,
  • Fungal keratitis,
  • Pityriasis versicolor,
  • Oropharyngeal candidiasis,
  • Onychomycosis,
  • Histoplasmosis,
  • Systemic Infections.

It is also used for antifungal prophylaxis in severely neutropenic patients when other treatments have proven ineffective.

Pharmacology of Itracon

Itracon is a formulation containing Itraconazole, an oral triazole antifungal agent known for its wide-ranging effectiveness and favorable pharmacokinetic characteristics. By inhibiting cytochrome p-450 enzymes, Itraconazole disrupts the biosynthesis of ergoesterol, a vital constituent of yeast and fungal cell membranes. Experience the potent antifungal properties of Itracon for optimal treatment outcomes.

Dosage & Administration of Itracon

Dosage guidelines for different infections are as follows:

  • Tinea corporis, Tinea cruris: 100 mg daily for 2 weeks.
  • Tinea pedis, Tinea manuum: 100 mg daily for 4 weeks.
  • Vulvovaginal candidiasis: 200 mg twice for 1 day.
  • Fungal keratitis: 200 mg daily for 3 weeks.
  • Pityriasis versicolor: 200 mg daily for 1 week.
  • Oropharyngeal candidiasis:
    • 100 mg daily for 15 days.
    • 200 mg daily for 15 days (for immunocompromised patients).
  • Onychomycosis: 200 mg daily for 3 months; or 200 mg twice daily for 7 days (course), subsequent courses to be repeated after 21 days interval; fingernails 2 courses and toenails 3 courses.
  • Histoplasmosis: 200 mg 1-2 times daily.
  • Systemic Infections: (Aspergillosis, Candidiasis and Cryptococcus infection when other drugs are ineffective) 200 mg once daily, increased in invasive or in cryptococcal meningitis to 200 mg twice daily.
  • Antifungal prophylaxis: To prevent systemic fungal infection in severely neutropenic patients 100 mg daily.

Contraindication of Itracon

Administration of the drug is not recommended for patients with a documented hypersensitivity to it. Pregnant women, individuals with severe hepatic disease, and those undergoing Rifampicin therapy are also advised against using the drug due to contraindications.

Adverse Reactions of Itracon

Instances of reported adverse effects include nausea, abdominal pain, dyspepsia, constipation, headache, dizziness, elevated liver enzymes, hepatitis, cholestatic jaundice, and peripheral neuropathy.

Interaction of Itracon

The metabolism of Cyclosporine and Warfarin is hindered by Itraconazole. Reports indicate interactions with Terfinadine, Phenobarbitone, and Midazolam. Stay cautious of these potential interactions when administering Itraconazole.

Precautions & Warnings of Itracon

Regular monitoring of hepatic enzyme levels is essential for patients with pre-existing hepatic function abnormalities. It is equally important to periodically monitor these levels in all individuals undergoing continuous treatment for over one month, as well as when any signs or symptoms indicative of liver dysfunction arise. Stay vigilant in assessing hepatic function throughout the course of treatment.

Use of Itracon in Pregnancy

Not recommended during pregnancy, unless otherwise indicated by a physician.

Use of Itracon in Lactation

Not recommended during lactation, unless otherwise indicated by a physician.

Pharmaceutical Precautions of Itracon

Ensure proper storage below 30°C, shielded from light, in a dry environment. Safely keep all medications away from children’s access.

Commercial Pack of Itracon

Itracon 100 capsule: Each box contains 6X4 capsules in Alu-Alu blister pack and an insert.