Bactrocin Ointment

Unit Price: ৳ 150.00

Pharmacology of Bactrocin Ointment :

Mupirocin is a naturally occurring antibiotic. It is an antibacterial agent produced by fermentation using the organism Pseudomonas fluorescens. It is active against a wide range of bacteria those responsible for the majority of skin infections, eg. Staphylococcus aureus including methicillin-resistant Staphylococcus aureus (MRSA) other staphylococci and streptococci. It is also active against certain gram-negative pathogens, like Escherichia coli and Haemophilus influenzae. Mupirocin inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase. Due to this unique mode of action, mupirocin demonstrates no in vitro cross-resistance with other classes of antimicrobial agents. Mupirocin is bactericidal at concentrations achieved by topical administration. However, the minimum bactericidal concentration (MBC) against relevant pathogens is generally eight-fold to thirty-fold higher than the minimum inhibitory concentration (MIC). 

Indications of Bactrocin Ointment :

 Bactrocin ointment is indicated for the topical treatment of impetigo due to: Staphylococcus aureus and Streptococcus pyogenes.

Dosage & Administration of Bactrocin Ointment:

A small amount of Bactrocin ointment should be applied to the affected area three times daily. The area treated may be covered with gauze dressing if desired. Patients not showing a clinical response within 3 to 5 days should be re-evaluated.

Interaction of Bactrocin Ointment :

 The effect of the concurrent application of Mupirocin and other drug products has not been

Precaution of Bactrocin Ointment :

 Mupirocin ointment is not for ophthalmic or intra-nasal use. If a reaction suggesting sensitivity or chemical irritation should occur with the use of Mupirocin ointment, treatment should be discontinued and appropriate alternative therapy for the infection instituted. As with other antibacterial products, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi, When Mupirocin is used on the face care should be taken to avoid the eyes. Polyethylene Glycol can be absorbed from open wounds and damaged skin and is secreted by the kidneys. In common with other polyethylene glycol-based ointments, Mupirocin ointment should not be used in conditions where absorption of large quantities of polyethylene glycol is possible, especially if there is evidence of moderate or severe renal impairment.

Use in Pregnancy of Bactrocin Ointment :

The drug is classified in Pregnancy Category B. Because animal studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Use in Lactation of Bactrocin Ointment :

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Mupirocin is used to a nursing woman.

Pediatric Use of Bactrocin Ointment :

The safety and effectiveness of Bactrocin have been established in the age range of 2 months to 16 years. Use of the ointment in these age groups is supported by evidence from adequate and well-controlled studies of Mupirocin in impetigo in pediatric patients.

Adverse Effects of Bactrocin Ointment :

The following local adverse reactions have been reported in connection with the use of Mupirocin

Storage of Bactrocin ointmen :

 Store below 25°C, in a dry place proteced from light. Do not freeze.

Commercial Pack of Bactrocin ointmen :

Bactrocin ointment: Each tube containing 10 gm ointment